Rihards Kuksiks on the other hand, displayed some hot shooting and scored on a trio of consecutive beyond the arc shots to expand the Devils' lead to 24-14 with 4:31 left in the half.
ASU reverted back to their offensive struggles and scored just two points the rest of the period. The half ended on a Taj Gibson dunk which was ultimately a prelude to the Trojan onslaught in the second stanza.
Two three pointers by Dwight Lewis gave the hosts their first lead of the game, 29-28, at the 16:44 mark. Harden finally sneaked into the scoring column with two free throws made, but USC tied the game at 40 apiece with7:28 left in the contest.
Then came the decisive stretch of the game where the Trojans went on a 11-2 run, capped off by a long range basket of its leading scorer tonight, DeMar DeRozan, who made it 51-42 with 4:34 left, and the hosts coasted the rest of the way onto their impressive victory.
Kuksiks paced ASU with 16 points, but his four three-pointers all came in the first half. Derek Glasser and Jeff Pendergraph had 13 points each. Harden who was 0-9 from the field tonight and missed his first three free throws, tied Pendergraph for the team lead in rebounding with seven.
ASU was 33.3% from the field and 12-20 from the charity stripe. They were dead even with USC at 29 rebounds each. DeRozan led all scorers with 22 points.
A tough road stretch continues for the maroon and gold as they face UCLA in Pauley Pavilion on Saturday at 1:45. With their confidence surely shot right now, Herb Sendek's team will have to regroup in a hurry and try a salvage their L.A. road trip with what would be an improbable victory.