Hollowell (26-3) gave up two hits in winning in relief. Serrano (17-9) held top-ranked Arizona to five hits.
UA squandered a big opportunity in the first, stranding three of the nine runners it left on base during the game. Autumn Champion led off with a bunt single, Courtney Fossatti walked, and ASU pitcher Desiree Serrano intentionally walked national home run leader Lovie Jung to load the bases. But Serrano got out of the jam by striking out Mackenzie Vandergeest and Jackie Coburn and getting UA starting pitcher Wendy Allen on a pop foul.
Phelan Wright led off the ASU second with a home run to left field to give the Sun Devils a 1-0 lead. A hit batsman and a single by Cheryl Evans put runners on first and second, but third baseman Coburn turned a 5-3 double play.
Singles by Jen McCard and Jennifer Forner in the top of the third helped chase Allen, who's been troubled by a hand injury most of the year, and UA brought in Hollowell for her fourth relief appearance of the year. Hollowell got a groundball out, intentionally walked Wright and struck out Adriana Garcia to end the rally.
The Cats (41-4, 10-1 in Pac-10 action) tied the score with an unearned run in the fourth. Lisha Ribellia drew a two-out walk, moved to third on an error and scored on Crystal Farley's single up the middle.
UA took the lead in the fifth. Jung walked, and to third when Serrano threw Vandergeest's sarifice bunt into center field trying to get Jung at seconde. Coburn hit a sac fly to give UA the 2-1 lead.
ASU (28-15, 5-6 in league play) threatened in the top of the sixth when Hollowell walked Kara Brun and Wright, got two outs, then walked Cheryl Evans to load the bases. A high Hollowell pitch got past catcher Vandergeest, but she chased it to the screen and flipped it to Hollowell for the tag on a sliding Brun at the plate.
Game One - UA 8, ASU 0
The top of Arizona's batting order collected nine hits to pace UA's offense and Alicia Hollowell threw a one-hit shutout over No. 12 Arizona State, 8-0, in college softball Friday night at Hillenbrand Stadium.
Autumn Champion singled three times, Courtney Fossatti singled four times and Lovie Jung homered and doubled to drive in four runs.
Arizona had successive singles by Champion and Fossatti to open the first, then ASU pitcher Desiree Serrano intentionally walked home-run Lovie Jung. The ploy worked as Mackenzie Vandergeest and Jackie Coburn hit into short-to-home fielder's choices and Wendy Allen struck out to end the threat.
Arizona batted around two innings later to blow the game open. Champion and Fossatti singled again, and this time ASU pitched to Jung and she smacked her 22nd home run of the year to give UA a 3-0 lead.
After walking the next batter, Vandergeest, Serrano (17-8) was pulled. Reliever Susan Aguilar gave up a single to Coburn, Allen advanced both runners with a sacrifice bunt and Lisha Ribellia hit a sacrifice fly to make it 4-0. Shelly Shultz doubled to right-center to make it 5-0.
The Cats picked up a couple more runs in the fourth. Fossatti singled again in the fourth and Jung doubled to right-center to drive in another run. After moving up on a ground ball, Jung scored on Allen's opposite-field single to left.
Crystal Farley singled with one out in the bottom of the fifth, Champion singled again and Fossatti singled to drive in Farley with the final run, on the mercy rule.
Hollowell won her 25th game against three defeats to break Becky Lemke's 1998 freshman record of 25 victories in a season.
Top-ranked Arizona improved to 40-4 and 9-1 in Pac-10 play. The Sun Devils dropped to 28-14 and 5-5. The two teams complete their two-game series Saturday at 7 p.m.