Sophomore All-SEC performer Lee Williams is tied for 66th after firing a 76 while sophomore Jonathan Dismuke and freshman Will Claxton both carded five-over par scores of 77 and are tied for 81st.
"I am extremely proud of the way Jay and Kevin played," SEC Coach of the Year Mike Griffin said following the round. "Jay played some great golf while Kevin played even par after the first hole on a very, very difficult golf course.
"We are right in the thick of things, and I am looking forward to Friday's pairing as we play in the morning wave before the greens become crusty. There is a lot of golf left to be played."
Second-ranked Clemson shot a 2-under 286 and has a five-shot lead over top-ranked Georgia Tech (291), the tournament's host. Tenth-ranked Tennessee is in third at 294 followed by North Carolina (295) and the East Regional's 22nd seed, Penn State (295), in a tie for fourth.
South Carolina is in sixth at 298 followed by the Tigers in a six-way tie for seventh at 299 with #3 Wake Forest, #19 Augusta State, Furman, Georgia Southern and North Florida. Fourth-ranked Florida and #11 Georgia are tied for 13th at 300.
UAB is in 15th with a 301 followed by Coastal Carolina (302), Jacksonville State (303), College of Charleston (304), William & Mary (305), VCU (306), Rhode Island (307), Duke (308), Michigan State (308), Virginia (313), South Alabama (313), Yale (314) and Iona (315).
Clemson's D.J. Trahan, one of the top amateur players in the country, fired a 3-under par round of 69 to take the individual lead, a shot better than Georgia Southern's Tyler McKeever, Penn State's Jim Fuller, Vanderbilt's Brandt Snedeker and Georgia Tech's Matt Weibring at 2-under 70. Weibring is the son of PGA Tour Veteran D.A. Weibring.
The top 10 teams in the 27-team field and top two individuals not on those qualifying teams advance to the NCAA Championship May 29-June 1 at the Ohio State University Scarlet Course.
The Tigers tee off in Friday's second round in the morning pairing on the tougher back nine at 6:57 am Central with Georgia and North Carolina. The third and final round of the 54-hole Regional is Saturday.