Freshman DeWanna Bonner led the Tigers with 14 points. She made 7-8 free throws and added a team high six rebounds.
The Tigers got 12 points from freshman forward Sherell Hobbs, who added four rebounds in a reserve role.
With a crowd of 12,771 watching the Lady Vols were led by center Tye'sha Fluker, who scored a career-high 22 points on 7-9 shooting from the field.
Candace Parker scored 11 points for UT and added 13 rebounds, five assists and three steals.
"We have been rebounding better in recent games," UT coach Pat Summitt said. "After losing Alexis (Hornbuckle) who was our second leading rebounder. Rebounding has been a challlenge for everyone. We have to do better. Auburn had two offensive rebounds, and that was a key. We had 15 offensive rebounds, and that gave us a chance for putbacks."
UT led 39-29 at halftime and outscored the Tigers 42-27 in the second half.
"I don't think we started the second half well enough and with enough energy and that really hurt us," Auburn coach Nell Fortner said. "I think we started the game with a lot of energy, but we just didn't start the second half well enough and it really showed on the defensive end."
Auburn was 14-17 at the foul line and 2-10 on threes. AU made 43.5 percent of its field goals.
The Lady Vols were 17-21 at the foul line, 6-19 on threes and hit 44.6 percent from the field to improve to 25-3 overall and 11-2 in the SEC.