The Tigers were led by sophomore guard Sherrell Hobbs, who scored 17 points while hitting 7-12 field goals. She added four rebounds, three steals and a blocked shot.
The Tigers also got 13 points from junior guard Tamela McCorvey who added three assists and three steals.
Sophomores Keke Carrier and Trevesha Jackson both hit 5-6 field goals while scoring 11 points. Carrier had six rebounds, one behind Whitney Boddie's team-high total.
Coach Nell Fortner's team outshot the home team 51.9 percent to 26.4 percent, which was enough to overcome a 51-40 rebounding deficit. Both teams turned the ball over 19 times. Both teams struggled at the foul line. The Tigers hit 15-30 free throws while Western Carolina made 16-25.
"I'm really proud of how we played tonight," Fortner said. "They were fighters out there. They never lost their composure, and they never quit."
Auburn held the Catamounts to 23.5 percent shooting in the first half as the Tigers took control of the contest.
The Tigers return to action on Wednesday at 6 p.m. with a home game vs. Alabama State.