The 27-yard pick-6 by Antonio Allen put a bitter end to Parker's career in Death Valley.
After going 7 of 17 with 117 yards and a touchdown, he was subbed out.
Tajh Boyd played the rest of the way and completed 10 of 18 throws for 73 yards.
"I think it was pretty decent. I did some good things. I feel like they recruited me for a reason. I went out there and made some plays. I got a little bit of a rhythm going," Boyd said.
Following the interception, Dabo Swinney figured it was time to make the switch, which came with just over 10 minutes left in the third quarter.
"I felt like [Boyd] needed the opportunity to go see what he could do," he said.
When asked about the substitution, Swinney said, "It was a decision that I felt like was best for our team, at that point."
After the game, Boyd said he didn't expect to play this week, after not taking a single snap with the first-team.
"I always want the best for Kyle. I wish he could have finished his last game here, but I think everything happens for a reason," Boyd said. "Hopefully, this will lead to some good things."
Offensive coordinator Billy Napier felt Boyd did well, considering the circumstances.
"He did some good things," Napier said. "I think we've got a lot to work to do. When they're open, he can make the throws. He did make some good decisions. It was evident he was doing what he was coached to do."
"For a freshman, I think he went out there and did as well as could have expected him to do."
Swinney liked how Boyd responded.
"That will be great, valuable experience for him as he gets ready to take the reins," Swinney said.
He declined to name a starting quarterback for the bowl game, but said it would "the player that gives us the best chance to win."
"Both of them will play—that's a pretty safe bet," Swinney said.
More time for Tajh Boyd?
CUTigers.com Top Stories
4-27 RECRUITING RADARIn our weekly Recruiting Radar, CUTigers Recruiting Analyst Gary McDaniel updates you on the latest news and intel on the Clemson recruiting front!
CUTigers.comThursday at 4:10 AM
TIGERS WIN 7-2, SWEEP C OF C!Reed Rohlman is 10 of his last 13 and upped his average to .413, going 3-3 with a HR, two doubles and a HBP, as #3 Clemson cruised past Monte Lee's alma mater, College of…
CUTigers.comTuesday at 7:40 PM
TIGERS WIN 11-0 TO TAKE SERIES!Alex Eubanks struck out 12 and walked none in a 116-pitch, complete-game 11-0 shutout of #17 Wake Forest in the first half of a doubleheader, putting #3 Clemson in position for…
SWEPT UGAIN!Tyler Jackson allowed just one earned run, and Chris Williams broke the game open with a 3-run homer to lead #3 Clemson to a 9-7 win over UGA for the season sweep!
ANOTHER 11TH INNING WALK-OFF WIN FOR TIGERS!#4 Clemson beat Charleston Southern 6-5 for its second 11-inning win of the season in walk-off fashion, thanks to the bull pen, Logan Davidson, Reed Rohlman and Rudy Cox, who…