Fisher learned Monday the ACC Media selected Florida State to win both the division and conference titles.
Clemson, of course, was picked second.
And on Sept. 24, the Tigers and Seminoles will open conference play against one another in Death Valley.
"I think it's a huge game. It's a conference game, which is your ultimate goal, first and foremost," Fisher said at the ACC Football Kickoff on Monday. "You win the Atlantic. You win the ACC. That's the first thing. And you have to learn how to win on the road.
"It's a very tough place to play. It's a huge game. It's going to be after a very emotional game, [before] we play Oklahoma. I think it is a very important game.
"Everybody talks about the Oklahoma game, but [Clemson] is just as important a game. It's going to be a great challenge. They've got a great team and great players."
Fisher, who's entering his second season as head coach at Florida State, believes there's a quality rivalry between the two schools.
"You talk about Florida and Miami, but Clemson is in our league, on that side," he said. "It's become a big game. We've been the last two teams that have won the Atlantic, represented the Atlantic the last two years. From that standpoint, it's a huge game."
Florida State hasn't beaten Clemson in Death Valley since 2001. Conversely, the Tigers have only one once in Doak Campbell Stadium since the Seminoles joined the league in 1993.
The Tigers lost Florida State last year, 16-13, on a 55-yard field goal as time expired.
Clemson-FSU rivalry growing
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