The Tigers (28-19) took a 1-0 lead in the two-game series against the Rebels (29-17) in the first meeting between the two schools since 2001.
Wilkerson's fifth blast of the season in the sixth inning broke the 1-1 tie, then a run-scoring double by Jay Baum and Weston Wilson's RBI groundout later in the sixth gave the Tigers a three-run lead. In the seventh inning, Wilkerson laced a two-run single to give Clemson a 6-1 lead.
Junior righthander Daniel Gossett (6-0) earned the win by allowing just two runs on seven hits with seven strikeouts in 8.0 innings pitched. Rebel starter Bryan Bonnell (5-4) suffered the loss, as he gave up seven hits, four runs and three walks in 5.1 innings pitched.
The two-game series concludes Monday at 6:30 p.m. at Doug Kingsmore Stadium.
Wilkerson, Gossett lead Clemson over UNLV
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