Choice, who is just a freshman, injured his knee during the first half of Clemson's 17-13 win over Boston College Saturday.
He finished his freshman campaign with 50 carries for 218 yards and a touchdown. Clemson offensive coordinator Chad Morris indicated after the win Choice was expected to be an instrumental part of the game plan at B.C.
"I feel bad for Adam, because he was really coming on, just hitting his stride," Swinney said in his weekly teleconference with the media. "It's a big, big loss for us. Between him and Zac Brooks, that's two really good players we're without. We still have enough to get the job done, but it's a still a big loss."
Redshirt freshman Wayne Gallman is now listed as the starter for this weekend's homecoming tilt against Syracuse.
Choice is the second running back to go down with a season-ending injury. The Tigers also lost Zac Brooks during preseason camp as well.
The other major injury news revealed Sunday concerned sophomore tight end Jordan Leggett. Leggett suffered a torn meniscus and MCL sprain in the win Saturday and will miss "the next couple of weeks," Swinney said.
Swinney also discussed the possible debut of redshirt freshman RB Tyshon Dye in the near future.
The Tigers' sixth-year head coach told CUTigers.com last week Dye would make the trip to Boston College but wouldn't play. With Choice out of the mix, Dye is listed on the depth chart at running for the first time - on the fourth team.
When asked if Dye could play this weekend, Swinney responded, "Ask me again on Wednesday. We'll watch him in practice and just see where he is. He's cleared from the doctor's standpoint, but there's the mental side, as well."
Dye injured his Achilles in February after suffering a back injury during the summer of 2013.
The Achilles injury typically takes between six to 12 months to heal. He is currently more than eight months removed from the injury itself.
"He practiced last week and did a lot, including inside drills," Swinney said. "We held him back a little, but this week we'll cut him loose. He's in good shape, and we'll just see what happens."
Dye, who is considered more of a power runner, was a four-star running back according to Scout.com coming out of high school and has been mentioned several times by the coaching staff as a player who could have started last season at running back, had he been healthy.
"We were hoping to play him last year," Chad Morris recently told CUTigers. "There's no doubt in my mind he could have helped us out."
Hopefully he can help the Tigers out soon- possibly as soon as this weekend.
Choice out with ACL tear
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