Morningstar wasn't a factor in the second half because twins Markieff and Marcus Morris took over, taking advantage of their size and power advantage in the post.
The brothers combined to score 42 points with 25 rebounds.
All five Kansas starters scored in double figures, led by Markieff Morris, who had 26.
Four of the Buffs' five starters scored in double figures, but they had almost no help from a thin bench. Alec Burks led CU with 15 points. Cory Higgins finished with 14 and fellow seniors Levi Knutson had 13 and Marcus Relphorde scored 12. Knutson and Higgins joined a large group of former Buffs who spent four or five years at Colorado without ever winning on the road against the Jayhawks.
Freshman Andre Roberson was the only Buff to score off the bench for CU. He finished with five points and seven rebounds.
The Buffs were out rebounded by 14 and made just two of 15 3-point shots. Kansas made 11 of 22 3-pointers and shot 52 percent from the field in the game.
Colorado made a small run in the second half cutting the lead to 13 at one point, but never seriously challenged the Jayhawks after intermission.
The Buffs dropped to 16-11 overall and 5-7 in Big 12 play. Kansas rebounded from a loss to Kansas State earlier in the week and improved to 25-2 and 10-2 in the Big 12.