Midway through the second half the Jayhawks led by 20 before Colorado began some trimming of its own.
Four Kansas players scored in double figures and the Jayhawks' depth once again proved too much for CU.
Playing the final Big 12 game of his career, senior Cory Higgins struggled badly. He made only one of 11 shots and scored just six points one day after taking over against Kansas State and scoring 28.
CU received an unusual contribution from point guard Nate Tomlinson who made three of four 3-point attempts. Freshman Andre Roberson also was significantly less effective against the Jayhawks compared with the Wildcats. He scored nine points with five rebounds.
The Buffs now wait for the NCAA selection show on Sunday evening to learn if they will get a ticket to the dance. Conventional wisdom says they have earned a spot and will likely be a No. 10 or 11 seed. The Buffs might even be able to play a game or two in the first and second rounds being hosted in the Pepsi Center in Denver. We'll find out Sunday.