A native of Centennial, Colo., Powers was a part of three Colorado Class 5A state championship teams at Highlands Ranch High School (2000-02) and was the starting point guard when the Falcons were ranked No. 1 in the nation in 2002. Powers was a teammate of UConn's Ann Strother on those Highlands Ranch teams. She averaged 13.6 points and 6.8 assists per game over her prep career including a personal-best 15.7 per game as a senior. Powers was a two-time Street & Smith's honorable mention All-American and a Parade honorable mention All-American in 2003.
Powers played in 41 games over two seasons with the Fighting Irish averaging 6.5 minutes per game. Notre Dame was 48-17 with Powers on the roster advancing to a pair of NCAA Tournaments, including a Sweet 16 appearance in 2004.