Colorado lost 27-11 to the Sooners on Nov. 2. In the first half, the Buffaloes lost two fumbles, had a pass intercepted, muffed a pooch kick and had a field goal blocked.
"We didn't give ourselves much of a chance," Colorado coach Gary Barnett said Monday. "You can't play a team like Oklahoma and expect to win when you turn the ball over."
Oklahoma quarterback Nate Hybl knows the Sooners did enough to win.
"The feeling I got was they left some plays on the field and we didn't finish the game like they were expecting us to," Hybl said. "We made enough plays and we did get a little conservative. I don't know how they reacted but we deserve a lot of credit."
No. 12 Colorado (9-3) had its toughest times early in the season. The Buffaloes lost their opener to Colorado State, then lost 40-3 to Southern California in the third game of the season before putting together a five-game winning streak that ended when Oklahoma beat them.
"This championship is won through the year," Oklahoma coach Bob Stoops said. "That's why the conference games count. They are sitting here with a great record and one loss (in Big 12) and they've beaten some awfully good teams. We were fortunate to beat them.
"It's who's hot now."
Hybl threw three touchdown passes against Colorado in drives that covered just 39, 24 and 9 yards.
"They feel they still have a lot to prove to us and we welcome that challenge," Hybl said. "It was a cold and rainy day so I look forward to a perfect setting. Defensively, they present a lot of different things. They'll bring a lot of people into the box and try to stop our running game."
Colorado enters the game with a three-game winning streak. They beat Nebraska 28-13 on Friday.
"(The Sooners) are a great football team and they played a great game against us at home," Colorado lineman Wayne Lucier said. "Now we have an opportunity to come back and play better and not turn the ball over and give them so many opportunities in our end of the field."