CSU stretched its lead to 14-0 when quarterback Grant Stucker connected with Mosure on a 13-yard pass late in the first quarter. After suffering public criticism from his head coach for sloppy play in training camp, Stucker looked like the best quarterback on the field at times. He completed 10 of 17 passes for 208 yards.
The Buffs looked flat and unprepared to play to that point but began to come around in the second quarter.
After CSU had taken a 17-0 lead, place-kicker Aric Goodman got the Buffs on the board with a personal best 54-yard field goal.
The Buffs were outgained 265 to 63 in total offense in the first half.
Colorado scored on its first possession of the second half when Cody Hawkins, now in his third year as the Buffs' starting quarterback, connected with Andre Simmons on a long passing play setting up and nine-yard Brian Lockridge touchdown run.
The Buffs appeared to be on their way to another score on their next drive, but Scotty McKnight was hit hard after making a catch near the CSU 15-yard line and fumbled. The play was first called a catch, but officials overturned it and ruled a fumble had occurred following a review of the replay.
CU couldn't find any offensive consistency and failed on 11 of 14 third-down opportunities. They didn't get back into the end zone until the final two minutes of the game when Cody Hawkins hooked up with McKnight on a two-yard scoring pass.
CU scored fewer than 20 points for the 20th time under Dan Hawkins and was outgained 376 yards to 251.
The Buffs now turn their attention to a short week of preparation for Toledo. CU travels to play the Rockets on Friday night.