Caprice Smith opened the game with a bucket before Krystal Hugelier hit three three-pointers to spot the Flames an early 9-4 lead.
Illinois-Chicago (5-6) built a seven-point advantage at 13-7, but the Blue Demons answered with eight consecutive points and regained the lead on a three by Missy Mitidiero with 12:09 left in the half.
Mitidiero's three-pointer was in the midst of a 19-3 run by the Blue Demons that ended with DePaul holding a 25-16 advantage at the six-minute mark. The junior guard scored 12 of the 19 points during the run as she drilled four three-pointers for DePaul.
The Flames didn't go away as they closed the deficit to a single point when LaShonda Grant scored on a layup with 1:05 until intermission. Holding the slim one-point lead, the Blue Demons closed the first half with a furious 7-0 run to take a 41-33 lead at halftime. Quigley started the run on a three-pointer with 48 seconds left before China Threatt hit a short jumper in the lane and Rubino grabbed a rebound and followed with the putback just before the halftime buzzer sounded.
The second half started with a Smith jumper for a 10-point lead and the DePaul advantage remained between 10 and six points over the first seven minutes. UIC cut the deficit down to three points on three occasions over the next four minutes before a 9-2 run by the Blue Demons pushed the advantage back to 10 points with 6:37 left.
With DePaul holding an eight-point advantage, the Blue Demons built their largest lead of the game at 72-56 behind free throws from Quigley and buckets from Smith and Threatt. In the final two minutes, UIC outscored DePaul, 9-2, for the 74-65 final.
Four DePaul players grabbed at least 10 boards while the team outrebounded UIC, 60-34. Rubino led the rebounders with 15 followed by Smith with 11 boards and Quigley and Erin Cattell gathering 10 rebounds each.
Quigley's 23 points and 10 boards led three double-doubles on the box score. She was followed by Smith with 16 points, 11 rebounds and Rubino with 11 points and 15 boards.
Mitidiero added 12 points while Threatt totaled nine points, four rebounds and four assists.
The Flames were led by Hugelier with 24 points and six three-pointers followed by Grant's 14 points.
DePaul heads south for the San Juan Shootout this week. The Blue Demons take on Loyola-Chicago on Wednesday evening before playing TCU on Thursday.
Postgame Notes: DePaul's 9-1 start marks the fourth time in school history with an 9-1 record to begin the season… no team has ever started the season 10-0… the nine-game winning streak is tied for the seventh-longest run in program history (sixth time)… at least three players grabbed at least 10 rebounds for the second time this season… Jenna Rubino moved into 29th all-time with 105 games and 20th all-time with 1,012 points… the program has won 25 consecutive games against Horizon League opponents and is 99-30 all-time against league teams… DePaul has won 31 straight in the series… overall, the Blue Demons hold a 33-5 series advantage.
Official Box Score
Three Double-Doubles Lead #17 DePaul Over UIC
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