Chad Millard added 15 points, 5 rebounds and 4 assists to send the Blue Demons their third straight season-opening loss. Dane Watts had 10 points and 9 rebounds.
Stinnett held up his hands and shook his head as he banked home his last 3-pointer from the right wing, giving Creighton a 70-58 lead with little more than two minutes to play.
Will Walker scored 13 points and Wesley Green added 10 for DePaul (0-1). Draelon Burns, expected to be the top option on offense for the Blue Demons, scored seven points on 3-of-16 shooting and failed to score in the second half.
Burns missed all five of his 3-point attempts after rimming out a corner shot at the end of last season that would have sent the Blue Demons to the NIT semifinals.
DePaul hit four of nine 3-point shots in the first half, but was 0-for-10 in the second half.
Creighton recovered after missing 14 of its first 16 shots as the Blue Demons quickly built a 20-4 lead.
The Bluejays cut DePaul's lead to four after a 13-point run, and tied the game at 32 when Josh Dotzler was left with a clear path in middle of the lane. The Blue Demons led 38-32 at the half.
Creighton scored the first seven points of the second half, and Stinnett's layup gave the Bluejays their first lead of the game at 39-38.
Stinnett hit all five of his 3-point shots in the second half after missing both attempts in the first.
Game Notes: DePaul wore black uniforms for the first time in school history... freshman Mac Koshwal became the first freshman to start a season opener under Jerry Wainiwright at DePaul... Koshwal's 11 rebounds were the most by a Blue Demon freshman since Andre Brown had 11 in his collegiate debut vs. Lewis in 2000... DePaul is now 74-11 all-time in season openers.
DePaul Drops Season Opener
We Are DePaul Top Stories
On Campus: Weekend of September 24thA number of the nation's top prospects will take official and unofficial visits this weekend. Who is headed where? Scout breaks down the key visits of the weekend.
Scout HoopsFriday at 5:07 AM
DePaul Learns Big East ScheduleCHICAGO – The Big East conference unveiled the 2016-17 conference schedule today as well as TV assignments for FOX and CBS coverage with the Blue Demons opening on the road at…
We Are DePaul09/13/2016
Hoops Recruiting Inside ScoopWhat's the latest on the top recruits in the country? Scout's basketball recruiting team -- Evan Daniels, Brian Snow and Josh Gershon -- break down the latest.
Updated 2018 Top 100The 2018 player rankings have been extended from a top 75 to a top 100. Marvin Bagley, a 6-foot-10 power forward, held on to the No. 1 spot, while Zion Williamson and Romeo…