J.J. Redick scored 24 points to lead the Blue Devils (17-1, 6-0 Atlantic Coast Conference), who have won 14 straight overall and 37 in a row at home.Sean Dockery went scoreless but had two big steals late as Duke remained the only unbeaten team in ACC play.
Tim Pickett scored 16 for the Seminoles (14-6, 3-4), who were trying to beat a top 10 team in three straight games for the first time in school history. Florida State, which had beaten North Carolina and Wake Forest in the last week, fell to 0-14 all-time at Cameron Indoor Stadium.
The Seminoles had beaten the Blue Devils at home in each of the past two seasons. But they had never fared well at Cameron, losing their 13 previous games by an average of 21 points per game.
They hung around most of the way Thursday, playing scrappy defense and giving Duke one of its toughest challenges since taking the No. 1 ranking two weeks ago.
The Blue Devils led by 12 at halftime and took their largest lead at 49-34 on a 3-pointer from Redick with 9:28 to play.
But the Seminoles answered with a 15-2 run, getting a three-point play fromAlexander Johnson and a 3-pointer from Pickett to cut the deficit to 51-44 with 3:22 left. Von Wafer then had a stickback and a 3-pointer that cut it to 51-49 with one minute left.
But Duhon had an answer.
Coming out of a timeout, he took the inbounds pass from Daniel Ewing near midcourt, dribbled to the left wing and fired a 3-pointer. The shot swished through with 36.4 seconds to go, giving Duke a 54-49 lead and setting the 9,314 fans here in a frenzy.
Dockery then came up with two big defensive plays. After Duhon's 3, Dockery stole Wafer's inbounds pass and was fouled. He missed the free throw, but added another steal on Adam Waleskowski's pass.
Redick added two free throws with 5.7 seconds left to seal it.
The Seminoles played solid defense throughout, contesting Duke shots with their man defense and holding the Blue Devils to 39 percent shooting. They also pulled down 20 offensive rebounds.
But Florida State shot just 30 percent and never could take advantage of the Blue Devils' offensive struggles.