The win evens Duquesne's Atlantic 10 record to 4-4; they are 14-7 overall. This game stopped two streaks: Duquesne two-game losing and Saint Joseph's six-game winning.
Duquesne had suffered a 74-59 loss at St. Bonaventure on Saturday, the fewest scored this season.
A reverse was in order as Duquesne made the extra pass, shot extremely well, hit from three-point land and outrebounded SJU 36-31.
The Dukes opened with an 11-3 lead, scored 19 straight points in the final minutes of the first half, and took a 49-27 lead to the locker rooms.
Saint Joseph's Pat Calathes scored 19 second half points to lead St. Joe's effort to get back into the game. But the Hawks, who were playing without their second leading scorer Ahmad Nivins, never got the margin into single digits.
The closest was 12 on Garrett Williamson's layup in the final minute that reduced the score to 100-88.
Saint Joseph's is now 15-6, 6-2 in Atlantic 10 play.
Saturday, it is Duquesne that will head to the other side of Pennyslvania for a 2:00 p.m. game against La Salle at the Tom Gola Arena.