Rix is expected to be out for possibly two weeks after suffering a right ankle sprain when he planted to make a cut while scrambling in the first quarter against the Tigers.
Sexton, a redshirt sophomore from Leon High School, stepped in and led the Seminoles to a comeback victory.
With Sexton now the starter, Weatherford, a true freshman from Land O' Lakes, moves into the backup role, possibly ending any hopes of a redshirt season.
"I really haven't had time to really think about it," a smiling Weatherford said on Monday afternoon.
"It just happened. I always knew I had to be ready, that's why I got here early this summer to start to prepare and learn the offense.
"I don't even know what we are going to do. We haven't even had practice yet, me being second string."
The personable Weatherford admits he's excited about the possibility of playing against the Tar Heels. Weatherford also figures his practice intensity must be elevated this week as well.
"Not that I haven't been focused, but now I definitely have a chance of being in on Saturday," Weatherford said. "It makes me real excited, of course, and makes me want to study even harder and I am anxious to start practicing."
Weatherford also repeated his thoughts on a redshirt season.
"The way I've tried to handle is I really don't care, to be honest," Weatherford said. "I trust the coaches -- that's why I am here."
FSU offensive coordinator Jeff Bowden says Weatherford has accelerated his learning curve through extra preparation in the film room.
"The thing he has done is he spends an extraordinary amount of time in the film room outside of meetings," Bowden said on Monday.
"He comes in on his own and he might watch a game two times after we played it, just to watch and see what Chris is doing and to see what Wyatt's doing. So, he has taken it upon himself to push his learning curve a little up. So, what he's done he has done for himself. But he can only get so far with that. Now, he's gonna have to start getting some team reps."
Weatherford believes watching extra video has helped him during practice.
"I've noticed when I got here I started watching film and then going out to practice it was a lot easier," Weatherford said.
"It's just the best way to prepare and it makes you comfortable out there so you can just react, you don't have to think."