Al Thornton, who came in averaging nearly 25 points over the previous four games, was held to 13 for the Seminoles (12-4, 3-3 Atlantic Coast Conference). But he got plenty of help from his teammates, with little-used Jerel Allen contributing 11 points.
He had 12 combined in the past five games.
It was that kind of night for Florida State, which got its second conference victory on the road after losing at home to North Carolina on Sunday night.
Justin Gray had 16 of his 19 points in the first half for the Demon Deacons (12-7, 1-5), and teammate Eric Williams finished with 12 points and 12 rebounds. Wake Forest shot only 35 percent from the field, including 9-for-28 in the second half.
The Seminoles were 11-for-20 on 3-pointers, including Wilson's 4-for-7 effort.
The Demon Deacons trailed for the final 35 minutes, and for much of that span, they were down by at least 10 points. Finally, they got a run going to get back in it.
Most of the damage came at the line, where Harvey Hale made four and Trent Strickland added two. Kevin Swinton followed up a miss by Hale for his only basket to cut the deficit to seven, and Gray had a chance to bring Wake Forest even closer.
But he clanged a pair of free throws off the rim following a media timeout, and Diego Romero later swished a 3-pointer on the other end to make it 58-48.
The margin was 12 before the Demon Deacons rallied again. Williams started a 9-0 run with a layup - his first points of the second half - and Strickland capped it with a 3 to bring his team within 62-59.
Again, the Seminoles came up with a clutch shot, with Wilson connecting from beyond the arc for a five-point advantage. Then Gray added one of his own a couple of minutes later and Michael Drum drove through traffic to score as he was fouled, and even though he missed the free throw, the Demon Deacons again trailed by only three.
They had one final opportunity in the final minute, but Williams lost the ball in the post, and Florida State close out the victory by converting 6-of-8 at the line.
Hale had 16 points for Wake Forest.
Florida State hold off Wake Forest 75-68
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