The Seminoles (16-4, 3-2 Atlantic Coaast Conference) led 30-16 at the intermission, then extended their lead to as many as 21 points even when the Cavaliers started making shots.
Virginia (7-9, 1-4) lost its fourth in a row since opening ACC play with an overtime victory at Georgia Tech. The Cavaliers finished the game just 17-for-48 from the field.
Soloman Alabi added 10 points for the Seminoles, who shot 50 percent for the game.
Sylven Landesberg led Virginia with 24 points, including 14-for-14 at the foul line.