All times listed are Eastern and the games are on Saturday unless otherwise indicated.
Georgia Tech at Notre Dame (3:30, NBC) - Charlie Weis breaks in a new quarterback against one of the country's best defensive coordinator's in Jon Tenuta. For Georgia Tech's offense, it's the ultimate mixed bag: no more Calvin Johnson, but also no more Reggie Ball.
Tennessee at Cal (8, ABC) - Cal looks for revenge after being humiliated last year at Neyland. This is the only matchup of two ranked teams this week and the only one between the Pac-10 and SEC this year.
Florida State at Clemson (8 Monday, ESPN) - FSU's "new and improved" Jimbo Fisher led offense debuts. Does anyone know if the coaches in this game are related? Wish the media would do a little digging and cover that angle more.
Wake Forest at Boston College (3:30, ABC/Gameplan) - Last year's ACC champs open on the road in new BC coach Jeff Jagodzinski's debut. One of two important ACC Atlantic division games in week one.
Oklahoma State at Georgia (6:45, ESPN2) - Challenging home opener for Bulldogs. Former Gator offensive coordinator Larry Fedora's Oklahoma State offense was one of only two to average more than 200 yards both rushing and passing per game in 2006.
Kansas State at Auburn (7:45, ESPN) - The Wildcats knocked off Texas last season, but otherwise were unremarkable in games with quality opponents. Auburn looks for a second consecutive win against a Big 12 North team after beating Nebraska in Cotton Bowl.
LSU at Mississippi State (8 Thursday, ESPN) - MSU hasn't stayed within 18 of LSU since 2000. This is the debut of LSU offensive coordinator Gary Crowton and a first look at how Matt Flynn will lead the team at quarterback.
Utah at Oregon State (10 Thursday, FSN) - A pair of bowl winners from last year. Beavers star receiver Sammie Stroughter has been out of practice most of August dealing with personal issues.
Marshall at Miami (noon, ESPNU) - Randy Shannon's debut as Canes coach. Marshall's missing last year's C-USA defensive player of the year Albert McClellan due to a knee injury.
Nevada at Nebraska (3:30, ABC/Gameplan) - Arizona State transfer Sam Keller debuts as Nebraska's starting quarterback. Wolfpack lost to Miami by just one in bowl game, and have a decent offense.
Missouri vs Illinois (3:30, ESPN2) - I'm sure Ron Zook's team is getting better and better, and if they're not it's correctable. Missouri's fans expect big things this year, so there's pressure on them in this one.
Tulsa at Louisiana-Monroe (7 Thursday, ESPN 2) - It's the first game of the year, which elevates it to this level. For Louisiana-Monroe, possible invitation to the White House since mascot name change to Warhawks has not yet materialized.
Washington at Syracuse (8 Friday, ESPN) - Washington has the toughest non conference schedule in the country this year, so Tyrone Willingham needs a win here badly.
ECU at Virginia Tech (noon, ESPN) - First game since April's mass shooting tragedy in Blacksburg should be an emotional scene
Virginia at Wyoming (2, Versus) - Two years ago The Sporting News put Wyoming's Joe Glenn on their cover as the coach everyone in college football would be trying to hire after that year. Oops.
Washington State at Wisconsin (3:30, ABC/Gameplan) - The Bill Doba Farewell Tour begins in Madison. Badgers should be able to run at will.
Arizona at BYU (5:30, Versus) - Sonny Dykes came over from Texas Tech to run Wildcat offense this year. Mike Stoops needs this one, because without a bowl trip he's done in Tucson.
Idaho at USC (10:15, FSN) - Sure, it'll be as competitive as your windshield versus a bug, but it's the last game on Saturday night which elevates it to this category.
Texas Tech at SMU (4 Monday, ESPN) - Mike Leach's offense is always entertaining, plus it'll be the only game on.
Murray State at Louisville (7:30 Thursday, ESPN 2) - New Cardinals coach J.D. Brookhart's happy Bobby Petrino wanted to be the guy to finally make Michael Vick a successful NFL QB.
Navy at Temple (7:30 Friday, ESPNU) - The Owls won a game last year, so they're not due to win again until 2009.
UAB at Michigan State (noon, ESPN2) - New coaches Neil Callaway and Mark Dantonio debut.
CSU vs Colorado (noon, FSN) - Buffs players who didn't "go play intramurals, brother" try to improve in year two under Dan Hawkins.
UCLA at Stanford (3:30, FSN) - Jim Harbaugh finally stops talking and starts coaching. The talking will prove to have been much more entertaining.
Iowa at Nothern Illinois (3:30, ESPNU) - Being played at Soldier Field. No one in America who's not an alum of one of the schools will watch this without a substantial wager being involved.
Baylor at TCU (6, CSTV) - TCU demonstrates yet again that the Big 12 took the wrong team as their 12th member when the Southwest Conference feel apart
North Texas at Oklahoma (7, FSN) - Sooners tune up for next week's game with Miami. North Texas known as Mean Green because Easily Defeated Green didn't rhyme.
Purdue at Toledo (7, ESPNU) - Relive Ed Zaunbrecher's magical work as Florida's offensive coordinator by watching him call plays for the Boilermakers. Better yet, don't.
New Mexico at UTEP (10, CSTV) - How many times a day do you think Mike Price reminds himself he could be at Alabama if he hadn't chosen to patronize a stripper who looked like Dee Snider?