"Every mistake we had was big," Murray, who finished 19 of 29 with 248 yards passing, said. "It stinks to give points away like that in such a big ball game."
Trailing 38-35 late in the fourth quarter, Georgia had the ball with a chance to tie or win the game.
On the first play of the series, Gamecocks freshman defensive end Jadeveon Clowney sacked Murray and caused the redshirt sophomore to fumble.
Senior defensive end Melvin Ingram, 6- scooped the ball at the 5-yard line and scored the Gamecocks' final and decisive touchdown.
"It was a good defensive call by them and not good ball handling by me," Murray said. "I probably could've tried to tuck the ball away faster and not let them grab me."
Murray's first turnover was in the third quarter. Trailing 21-20, Murray looked to hit tight end Orson Charles with a pass over the middle.
Instead, South Carolina linebacker/safety Antonio Allen stepped in front and intercepted the pass, returning it 25 yards for a score.
"There was pressure and a tight window," Murray said of the play. "You have to put those throws right on the money, and I didn't."
"Just too many giveaways," coach Mark Richt said.
The costly mistakes overshadowed a successful day for Murray. He led the offense on seven scoring drives—five touchdowns and two field goals.
Still, it was what Murray gave to South Carolina that stuck with him the most following the game.
"In all three facets of the game today, we looked awesome," Murray said. "To just give the game away like that, you can't do that in the SEC. You can't do that against a great team like South Carolina."
A swing in momentum
South Carolina got the best of Georgia in a show of special teams gamesmanship in the second quarter.
Receiver Rantavious Wooten's receiving touchdown gave the Bulldogs a 13-7 lead with 3 minutes to play in the first half.
The play would have given Georgia excellent field position and sustained positive momentum.
But Rambo, a junior safety, was flagged for offsides just prior to the kick, negating the recovery.
"I still don't know," Rambo, who had six tackles and an interception, said. "I still don't know what happened. I knew the flag was for offsides, but I didn't know who it was on or if I was or what."
Georgia then kicked off to South Carolina and forced a three-and-out.
On fourth-and-seven from the South Carolina 32, the Gamecocks ran a fake punt, snapping the ball to 6-2, 276-pound defensive end Melvin Ingram who was lined up in the backfield.
"He got it and took off with it," said cornerback Brandon Boykin. "We didn't discuss a fake, so that was on us. We didn't expect it."
Ingram rumbled off the left side of the line, breaking two tackles on his way to a 68-yard touchdown score.
The run was Ingram's first career touchdown and the first of two on the night. The play marked the first successful fake punt allowed by Georgia since Vanderbilt's Brett Upson had a 7-yard run for a first down in 2009.
"It's something that happened, but we were still in the game in spite of it," Boykin said.
Georgia was able to recover from the play, taking a 20-14 lead after a third quarter Isaiah Crowell touchdown catch.
Last minute decisions
After Georgia's final score with 2:15 remaining in the game, Richt elected for an on-side kick down 45-41 despite having three timeouts left.
He thought about kicking to South Carolina and trying to force a punt, but an injury to linebacker Christian Robinson left Richt weary.
"We're already immature at that position," Richt said. "At that moment, we weren't sure if Christian could play."
South Carolina recovered the kick and converted a first down to run out the clock.
The Bulldogs were already missing starting linebacker Alec Ogletree due to foot surgery earlier this week. The severity of Robinson's injury is not yet known.
This and that
Boykin saw action on defense, special teams and offense for the second straight week. He had two tackles, one interception, 14 rushing yards and 184 kickoff return yards on a school record seven kickoff returns… Senior kicker Blair Walsh tallied nine points to move into third place all-time in school history with 315 career points, passing Herschel Walker who had 314… Georgia wore black #23 decals on the back of its helmets Saturday with the initials "J.E." above the number. The initials stood for Valdosta native James Eunice, who was expected to be a walk-on this fall before drowning in an accident earlier this year… Three Bulldogs made their first career start against the Gamecocks: Redshirt sophomore outside linebacker Chase Vasser, redshirt sophomore offensive guard Dallas Lee and freshman inside linebacker Amarlo Herrera. Herrera is the second true freshman Bulldog to start a game this year after wide receiver Malcolm Mitchell started the season opener versus Boise State.