Both teams are throwing their aces. The Hoosiers will go with lefty Joey DeNato, who is 7-1 with a 2.43 ERA. His last time out, last Friday against Morehead State, DeNato became IU's all-time career leader in wins with 31. He is also IU's all-time leader in strikeouts with 257.
He will face righthander Mick Van Vossen, who is 5-1 with a 2.55 ERA.
The three-game series will continue Saturday with a 2:05 p.m. first pitch and Sunday with a 1:05 p.m. start.
Indiana (22-11, 8-1 Big Ten) is alone atop the conference standings heading into the weekend and has swept its last two conference series', both on the road. IU beat Ohio State and Iowa three games each over the past three weeks.
Overall, the Hoosiers have won 10 of the last 11 games. Junior All-American catch Kyle Schwarber has a 14-game hitting streak while senior third baseman Dustin DeMuth has reached base safely in 30 games in a row.
Michigan State has a record of 20-14, including a 5-4 mark in conference play.
IU's staff earned run average leads the Big Ten this season at 2.71. In Big Ten play, that ERA drops to 1.89. IU has had four of the top 10 individual ERAs in the conference to date, though one of those is Kyle Hart at 2.29. Hart is out for the season after it was revealed last week he will have Tommy John surgery.