Larry Eustachy scored his 250th career victory as a head coach as ISU improved to 7-1 on the season. Eustachy is 91-46 during his tenure in Ames and 250-132 overall.
Eustachy's team fell behind by four points in the early going and pulled ahead 17-16 before starting its decisive run.
The Cyclones first used a 13-2 surge to pull ahead by 12 points, using a streak of nine straight missed shots from Savannah State, then added 12 unanswered points to go up 42-20 just before halftime. While its opponent suddenly went cold, ISU wrapped up the first half by hitting 9-of-11 shots from the field.
ISU outrebounded the Tigers 50-36, getting 15 of those from Jackson Vroman. The junior forward also added eight points on 4-of-8 shooting.
The Cyclones have a week off before hosting Drake next Sunday at 1 p.m.