The beginning of the game saw both teams make small runs only to be answered by the opposing team.
ISU scored the first five points of the game but the Cowboys scored nine straight to go on top 9-5 three minutes into the game. ISU tied the game on a three from Lucca Staiger and took the lead on a Craig Brackins' jumper with 8:39 left in the half, giving him 1,000 career points. Brackins is the 27th player in school history to reach the milestone and just the third player to do so in his sophomore season, joining Jeff Grayer and Curtis Stinson.
The Cyclones led by seven (36-29) with 1:34 remaining in the opening half following Jamie Vanderbeken's second 3-pointer. OSU closed the gap to three (38-35) at the half behind strong play from Moses, who scored eight of the Cowboys' final 10 points.
Brackins finished the opening frame with 15 points and 10 boards, giving him his 15th double-double of the season. The sophomore also became just the third player in school history to record 600 points and 300 rebounds in a single season.
In the second half, Iowa State held a four-point lead at 48-44 following Vanderbeken's fourth 3-pointer of the game. The Cowboys responded, going on an 11-2 run that was sparked by Keiton Page's three ball with 13:42 remaining in the game.
The Cowboys then jumped on the back of Muonelo, who scored 13 points in the period. OSU extended its lead to 10 points (67-57) after Muonelo's third three of the half and never looked back on its way to the 14-point win.
Brackins finished with a game-high 23 points and 12 rebounds. Vanderbeken added 12 points and Staiger and Garrett finished with 11 and 10 points, respectively.
James Anderson was one of three Cowboys joining Muonelo and Moses in double-digits. Anderson had 14 points in the game while Terrel Harris and Byron Eaton finished with 12 and 11, respectively.
The Cowboys held a 34-8 edge on points in the paint.