However, it's not an impossible feat. Even, a Terry Allen coached Kansas team went into Lubbock and stole a win, which they did in 2001.
The Jayhawks (1-8, 0-6) haven't played in Lubbock since Halloween 2009, when a 21-21 game spiraled out of control in the final quarter, as the Red Raiders handed KU a 42-21 loss in one of the games that signaled the beginning of the end for former coach Mark Mangino.
Much has happen since KU's last trip to the south plains of Texas.
Today, the Jayhawks are far removed from that time and look to start fresh.
A year ago, the Jayhawks built a quick 20-0 lead in Lawrence, before giving it up just as quickly in a 45-34 loss.
This year, Kansas has a new coach in Charlie Weis and the Red Raiders (6-3, 3-3) are stronger in the third year under coach Tommy Tubberville.
Ironically, Tech is led by quarterback Seth Doege, who started that 2009 game. Now a senior, Doege has been stellar in final year in Lubbock. Through nine game, he's thrown for 31 touchdowns and eight interception and nearly 3,000 (2,869 to be exact) yards.
Running backs Kenny Williams, Eric Stephens and Sadale Foster have combined for over 1,300 yards, with Williams leading the way at 575.
Eric Ward leads a balanced receiving corps with 643 yards and 10 touchdowns. Darrin Moore has 548 yards and eight scores.
However, the biggest signs of the Red Raiders being a Tommy Tubberville team is the defense. Texas Tech is no longer a team that just wins in shootouts. Yes, they can still light up the scoreboard, but it's the defense that grabs attention now.
Texas Tech is now giving up just and average of 314 yards per game (188 passing 126 rushing), which ranks 18th nationally.
"They are as strong as any team we will play against up the middle," Weis said.
Defensive tackles Kerry Hyder (6-2 281) and Delvon Simmons (6-5 290) will test the strength of the Kansas offense, which is the run game. This will be one of the biggest matchups of the game.
Regardless, it's same story for Kansas. Try to cause some turnovers and avoid making mistakes. Then, hope to slow down the opponent.
While, Kansas has not been very good on the road at all, a win would go a long way towards morale as the season draws to a close. In their minds, there's no better time to turn it around than now.