Kentucky, which advanced to the Final Four on Sunday with a Midwest Region finals win over Michigan, has yet to confirm the move.
Last year, he primed himself for a head coaching position by leading the Dominican Republic National Team to a qualifying spot in the 2014 FIBA World Cup in Spain.
Antigua is known as one of the top recruiting assistants in the nation. He has helped Kentucky sign five consecutive top-ranked classes. The Cats' 2014 class is currently rated No. 2.
During his time with UK, the Wildcats has won a national championship, earned three trips to the Final Four, and played in an Elite Eight.
The USF position was originally expected to be filled by former Wildcat Steve Masiello, who led Manhattan to the NCAAA Tournament this season, but the offer was rescinded when it was discovered he did not complete his degree at UK.