The No. 12 Wildcats (23-12, 7-7 SEC) pounded out 15 hits in the win at Cliff Hagan Stadium. UK batted around in the sixth inning, plating nine runs to blow what had been a pitchers' duel wide open.
Reed's NCAA-leading 14th home run came in the nine-run inning, and the national midseason player of the year just narrowly missed hitting another with a warning-track fly ball in the seventh inning.
"(Dylan) did a great job of pounding the strike zone once he got to 2-2 and full count," UK head coach Gary Henderson said. "A lot of pitches, a lot of deep counts, only walked one guy… I thought he did a really nice job of competing deep in the count and forced them to swing the bat."
Freshman Logan Salow came on in a first-and-third jam in the seventh, getting a double play to end the inning on just two pitches. Zach Strecker started the eighth, working the final two innings, allowing a hit and striking out two.
The Cats – who lead the SEC in nearly every offensive category also got two-hit games from Micheal Thomas, Ka'ai Tom, Storm Wilson, Thomas Bernal and Matt Reida. Missouri (16-17, 5-9 SEC) saw starter John Miles work five innings, allowing four runs on eight hits with three walks and three strikeouts. Miles (2-4) gave way to Andrew Schwaab, who was tagged for six runs in UK's sixth-inning explosion.
The series will conclude on Sunday at 1 p.m. ET at Cliff Hagan Stadium. The game will be televised live on CWKYT-TV and will be delayed on Fox Sports South, starting at 4 p.m. ET.