Anderson (2-2) allowed three earned runs over seven innings of work, scattering nine hits and one walk while striking out 10. The USA Collegiate National Team member also went 3-for-5 at the plate with two RBI.
Kentucky (23-13, 7-8 SEC) could not get its bats going less than 24 hours after pounding Mizzou 12-0 in Game 2 of the series. Leadoff man Austin Cousino collected three hits, but the Wildcats' 3, 4 and 5 hitters struck out five times and left five runners stranded.
Midseason national player of the year A.J. Reed saw his SEC home run streak end at five games, going 1-for-4 with an RBI on the day.
UK starter Andrew Nelson (1-3) worked six innings, allowing 10 hits and four runs, walking three and striking out two.
Gary Henderson's club will return to action on Tuesday, traveling to No. 10 Louisville for a 6 p.m. ET game at Jim Patterson Stadium.