The Bulldogs' record-setting senior quarterback passed for 348 yards and three touchdowns and rushed for 117 yards and three more scores in Mississippi State's 42-16 thumping of the Wildcats.
Prescott helped turn what was a four-point game with under three minutes left in the first half into a blowout as Kentucky failed to come up with any answers to his impressive dual-threat skills. Mississippi State (6-2, 2-2 SEC) finished with 586 yards of total offense.
"We really did play a complete game," MSU head coach Dan Mullen said. "... That was a heckuva win. Kentucky's a good team that has really come along."
It marked Mississippi State's seventh consecutive victory over the Wildcats, the annual cross-division rival.
Kentucky (4-3, 2-2 SEC) did little right after a competitive first quarter. The Wildcats were plagued by three turnovers, including two interceptions by starting quarterback Patrick Towles and one by backup quarterback Drew Barker on the second pass attempt of his UK career.
In this AllWildcats Rapid Recap feature, we touch on the highlights from the game...
What Went Wrong:
Almost everything from UK's perspective. A competitive game late in the second quarter spiraled out of control after an odd sequence that saw a 49-yard field goal by Austin MacGinnis wiped out by a timeout call from the Wildcats' sideline. It likely prevented a delay of game penalty, but UK head coach Mark Stoops vehemently protested the play with the officiating crew during the timeout. MacGinnis subsequently missed the second attempt, and the Bulldogs responded by driving 69 yards on five plays to stretch their lead to 21-10 with 1:34 to go in the half. Four plays later, Towles was intercepted by MSU's Taveze Calhoun on a deep pass. It took the Bulldogs only three plays to get back in the end zone again on a 20-yard run by Prescott. In the blink of an eye, a four-point game became an 18-point game. The Cats threw gas on the proverbial fire in the second half, dropping passes, committing penalties and hurting their chances with some puzzling play calls.
By The Numbers:
0 - Touchdown passes by UK over the last two weeks against Auburn and Mississippi State.
1st - Interception of the season by MSU's Prescott, breaking a school-record streak of 288 pass attempts without one. UK's Chris Westry ended the streak in the second quarter, preserving the record (325) held by former Wildcat quarterback Andre Woodson.
7th - Unlucky week for the Cats, who lost their seventh game last season 41-3 at LSU and dropped their seventh game during the 2012 season 49-7 at Arkansas.
95 - Rushing yards for UK's Stanley "Boom" Williams, who became the 35th player in school history to reach the 1,000-yard career rushing mark.
204 - Rushing yards for Mississippi State.
"Obviously not a very good night. Didn't play very good, didn't coach very good. Obviously that's not the result we're looking for... That's one football game that we're not very proud of, but there's nobody that's gonna sulk or pout or any of that." - UK head coach Mark Stoops.
Kentucky returns to action on Saturday, Oct. 31, for a Halloween showdown with Tennessee. The Volunteers dropped a 19-14 decision on Saturday afternoon at No. 8 Alabama.