The Cardinals were just nine outs from advancing into the NCAA Tournament regional final but saw the lead to UAB fizzle.
The Blazers scored four runs in the bottom of the fifth and added two more in the bottom of the sixth to rally and beat the Cardinals.
And then things fell apart against UCLA.
UCLA pounded out 12 hits and scored three runs in the first inning, nine in the second and six more in the third inning to grab an 18-0 lead.
Caralisa Connell (25-5) gave up five hits and walked seven batters in three and two-thirds of an inning. Rachel LeCoq came in and pitched a third of an inning, giving up five runs on five hits and hitting a batter.
"We just had no pitching," U of L coach Sandy Pearsall said. "We lost our pitching. We knew we were in trouble after our earlier game and it was going to be a battle because we really extended as much as we could with Rachel (Le Coq). In this game if you don't have pitching it becomes a very short - or long - game."
The ending was might long for the Cardinals.
U of L ends the season at 48-13 after making it to the NCAA Tournament for a 10th consecutive season. The Cardinals have never advanced past the regional.
"It isn't the end we wanted, but I think we can be very proud of what they accomplished this year," Pearsall said. "But there's nothing to hang your head about at this point. Things happen sometimes."