Led by Montrezl Harrell's 20 points, the Cardinals had five players in double figures. Highlighted by 7 dunks, Harrell was a near perfect 9 of 10 from the floor.
Senior guard Russ Smith had 17 points in just 19 minutes of action.
The game was slowed by a freqent whistle as the hand-checking rules change was evident. The two teams combined for 46 first half free throws and 88 overall.
Louisville's poor night at the charity stripe was the team's only glaring subpar effort. The team combined to convert just 57% (32-56) of its free throw attempts.
The Cardinals never trailed and were never threated in the game. U of L led by 18 midway through the first half and held a 49-33 lead at the break.
Led by Terry Rozier's 18 points, the trio of new guards continued to impress. After scoring just two in the first half, Chris Jones finished with 16, while Anton Gill contributed 13. Rozier also led all with 9 rebounds.
Redshirt freshman Mangok Mathiang had a solid outing, scoring 8 points on 4 of 5 shooting, while also pulling down 7 rebounds.
Louisville shot 58% from the floor, while limiting KWC to just 33% shooting. Jones, Rozier and Gill each hit a pair of three-point attempts and the team combined to hit 7 of 19 beyond the arc.
Louisville's defense, which didn't convert a foul while in the press, forced 24 turnovers and converted that into 28 points. U of L outscored KWC 52-26 in the paint.