The winless Huskies have struggled throughout the season and are currently under the direction of interim head coach T.J. Weist after firing Paul Pasqualoni following a loss at Buffalo on September 30.
While UConn has had difficulty finding success this fall, they do return a pair of players that are performing well despite the losses.
"I don't think their record really shows how good they can be," said U of L head coach Charlie Strong. "You look at their running back McCombs, he gave us fits last year. Then if you look at the defensive side of the ball, Smallwood is back at defensive end and we couldn't block him at all."
Last season the Huskies surprised the Cardinals at Papa John's Cardinal Stadium by claiming a significant upset with a 23-20 triple overtime victory.
The stinging loss from last year still lingers in the minds of the Cardinals making them more aware that upsets can easily happen.
"They know that now because I talk about it enough," said Strong. "They understand just how important games are. We're not in a position to go waste an opportunity because we only get so many."
The Friday night game is scheduled for an 8:30 p.m. kickoff at Rentschler Field in East Hartford, Conn., and will be broadcast nationally on ESPN2.