Smith turned into an All-American defensive end and on Thursday night he was picked in the first round of the NFL Draft.
The former U of L sack leader was the No. 26 pick of the draft by the Philadelphia Eagles.
"I just want to go somewhere I can play and help out, I want to win," Smith said earlier on Thursday. "I'm just excited for the opportunity to play in the NFL."
The 6-foot-3, 260-pound Smith, who can also play linebacker, became the 10th first-round draft pick in school history. He was the second of three first-round picks on the night.
Smith was recruited as a quarterback and moved to the defensive side of the football in 2010. And his transformation has been well documented with the Cardinals.
As a senior, Smith led the nation in sacks with 14.5 and led the Cardinals with 17.5 tackles for loss. The Cardinals led the country in sacks, total defense and rushing defense.
Smith was named AAC Defensive Player of the Year and finished with 41 tackles. He was named to a number of All-American teams.
Smith, who played as a true freshman, finished his career with 24.0 sacks, which ranks seventh in school history and also finished with 32 tackles for loss, which is tied for sixth all-time in school history.
"I always tell teams that I first bring a winning attitude and a winning attitude in the locker room," he said. "I am going to be someone you can count on. I want to be one of those guys who becomes a Pro Bowler, I want to be one of those players who becomes a legend."