The 6-foot-2, 303-pound Miller was taken with the No. 81 pick of the draft by the Buffalo Bills where he will join two other former U of L players.
Linebacker Preston Brown was a third-round pick last season, while center Eric Wood was a first-round pick in the '09 draft by the Bills and is a starter.
"He has long arms, huge hands and tremendous upper-body strength," ESPN draft analyst Mel Kiper said. "He has a real chance to be a starter in this league."
Miller spent two days with the Bills in March. He started 47 games at Louisville and all of those starts came at the left guard position.
BuffaloFootballReport.com reports the Bills are "likely to have an open competition at left guard with Chris Williams and Cyril Richardson posing as Miller's competition."
Miller's known for his upper body strength and is seen as a good fit in a power-running offense. He has a chance to start from day one.
After starting 10 games or more in each of his four seasons at Louisville - including being one of only five true freshman in the country to start along offensive lines in 2011 - Miller drew particular attention from NFL front offices at the East-West Shrine game in January. Scouts raved about his power during the week and Miller helped open a hole for former teammate Dominique Brown to score the game’s only touchdown.
He kept that momentum going in Indianapolis, running his 40-yard dash in 5.33 seconds at more than 300 pounds.
And now he's a member of the Bills organization.
AnalysisMiller had a big year in 2014 and actually led the ACC with 125 knockdown blocks and a 92.38% blocking grade. That’s outstanding. Starting at left guard for the entire season Miller only allowed two sacks. He’s 6-foot-2, 303-pounds and is very strong, especially in the lower body. Miller has an excellent initial punch and plays with a tough and relentless attitude and effort.
Dave-Te' Thomas Player Evaluation