Louisville is a 14-point favorite over host Syracuse for the Friday night game in the Carrier Dome.
The Cardinals racked up 663 yards of total offense and Lamar Jackson accounted for a school-record eight touchdowns in the opener last weekend against Charlotte, a 70-14 win.
But heading into the first ACC game of the season, Cardinal Authority has the key matchup of the game between the Cardinals and the Orange on the defensive side of the ball - U of L's dime package vs. Syracuse's offense.
U of L coach Bobby Petrino said the Orange "really play fast."
The up-tempo style employed by new coach Dino Babers for the Orange will be countered with Louisville's new-look 'dime' package on defense that has safety Josh Harvey-Clemons playing a linebacker role, lining up in different spots on the field.
The dime package also puts Zykiesis Cannon onto the field for the Cardinals in the secondary.
"It’s the reason that we put (the dime) in was because in these first two games you’re basically playing spread offensives and four wide receivers in a bunch so that’s the reason we were in it last week," Petrino said. "You’ll certainly see it again this Friday night."
Harvey-Clemons can adjust to different roles, which helps the defense against the offense that tries to run extra snaps. The dime package allows the Cardinals to adjust without having to change personnel.
And it helps that Harvey-Clemons is one of the team's best players He had five tackles in one half against Charlotte.
"I thought he did a really nice job,” Petrino said. “He slips blocks, and he understands schemes, and he’s a really good tackler. He’s got good match-ups in his cover skills, and, it’s like you said, we now have him playing three different positions, so he has great knowledge of our schemes. But he’s just a really good football player. He knows what offenses try to do. He doesn’t hesitate, he makes his decision and goes full speed with it, so I think you’ll continue to see him play fast and make a lot of plays for us.”
If Harvey-Clemons makes a lot of plays this week, the Cardinals will have success against the Orange.