When the University of Louisville hosts Duke on Friday night in Papa John's Cardinal Stadium it will mark just the second matchup between the two schools and the first in Louisville.
The previous matchup was a Louisville blowout - a 40-3 win over the Blue Devils on Sept. 7 of 2002 in Durham, N.C.
Former U of L quarterback Dave Ragone threw two touchdown passes and tight end Ronnie Ghent caught a TD pass from Ragone and also one from Stefan LeFors in the victory.
The Cardinals defense had a safety early in the game to go ahead 2-0 and blocked a punt that was recovered for a touchdown by Brandon Johnson later in the game. U of L was up 26-0 at one point.
The two schools were to meet four times between 2002 and 2009. But after the blowout win for U of L, the Blue Devils opted out of the final three games.
The schools are not scheduled to play again until the 2021 season when U of L will visit Durham.