Each week during the football season, Cardinal Authority breaks down the football opponent for the Louisville Cardinals.
And this week it's the injury-riddled Duke Blue Devils visiting Papa John's Cardinal Stadium.
The Blue Devils will play Louisville on Friday night with backup quarterback Daniel Jones - a redshirt freshman - running the show on offense under center for Duke.
The key matchup for the week is Jones against the Louisville secondary.
Jones has completed 62.3 percent of his passes for 1,455 yards and seven touchdowns in the first six games, but he has also thrown eight interceptions on the season. Duke coach David Cutcliffe said the key is to not turn the ball over.
On the other side, it's the Louisville secondary that has been ballhawking for the Cardinals.
Louisville had a season-high three interceptions in the loss to Clemson two weeks ago and has 49 picks since 2014, which is tops in the nation.
"It’s difficult to drive the ball on these guys so you’re going to have to take and hit shots," Cutcliffe said. "That’s the only way you’re going to score a point. Those have to be calculated and come without turnovers."
Cutcliffe said his team will need a solid effort to come up with the victory.
"This is a huge and monumental challenge for us," Cutcliffe said. "Teams have tried to stay on the field with them, and that’s the bottom line when you play them. We have to work smart and minimize errors to be able to have a chance against a team like Louisville."