The series between Louisville and Virginia has only been four games.
But those four games have been nailbitters with the outcome a combined 12 points, including a seven-point win by U of L last season. The series is tied at 2, including the 38-31 win by U of L last season at home.
The fifth game in the series will kickoff at 12 p.m. on Saturday in Charlottesville, Va.
The first game of the series was in 1988 when the Cardinals pulled out a 30-28 victory. In that game, Ron Bell kicked a 39-yard field goal with 10 seconds left to give the Cardinals a victory. Bell was used as the kicker after Howard Schnellenberger replaced then freshman Klaus Wilmsmeyer, who had missed two extra-point conversions. At the time, Schnellenberger called the victory "one of the greatest of all time" for the Cardinals.
One year later, Jake McInerney kicked a 37-yard field goal as time expired to give the Cavaliers a 16-15 win in Charlottesville. Browning Nagle threw for 194 yards and one TD and Bell had given the Cardinals a 15-13 lead with a 27-yard field goal on their final possession.
It was a field goal two years ago in Charlottesville with 3:41 left by Ian Frey that lifted Virginia to the 23-21 victory. Louisville fell behind 20-7 but Will Gardner's TD pass to James Quick with 6:59 left gave the Cardinals a 21-20 lead.
Quick then fumbled a punt when he was bumped into by a teammate, leading to the Frey field goal.
Last season, the Cardinals recovered an on-sides kick late to hold off the Cavaliers. Brandon Radcliff ran for 148 yards and two TDs, while Kyle Bolin threw for 139 yards and one TD and Reggie Bonnafon also threw for a TD.
Louisville quarterback Lamar Jackson rushed one time for 45 yards.