Louisville will also play home games against Cincinnati, South Florida and Connecticut with road games at Temple, Kansas State, Syracuse, Rutgers and Pittsburgh and a neutral site Friday night game against Middle Tennessee State at Aldelphia Coliseum in Nashville, Tenn.
"We have another challenging schedule that our players, coaches and fans will enjoy," said head coach Bobby Petrino. "We play at Kansas State for the first time and we have Kentucky, Miami and West Virginia at home for our fans. It's going to be a tough schedule, but I know our players will be excited about what's in front of them."
The Cardinals will kick off Bobby Petrino's fourth campaign on September 2 at home against intra-state rival Kentucky before traveling to Philadelphia, Pa., to face Temple on September 9. Petrino is 3-0 against the 'Cats and also defeated Temple, 21-12, in 2003.
Louisville's non-conference schedule is highlighted by a home game with national power Miami (Fla.) on September 16, to face the Hurricanes in Louisville for the first time since 1984. In 2004, the two teams played one of the most exciting games of the season, with Miami coming out ahead 41-38 at the Orange Bowl. Louisville has never beaten Miami, trailing 0-9-1 in the series.
Louisville will hit the road again on Saturday, September 23 to face Kansas State in Manhattan, Kan. This will be the first meeting between these schools.
The Cardinals will not play on Saturday, September 30, their first off week of the season, but returns to action on Friday, October 6 when the Cardinals play Middle Tennessee State in Nashville, Tenn. at Adelphia Coliseum, the home of the Tennessee Titans.
The BIG EAST Conference schedule opens on October 14, when Cincinnati comes to Papa John's Cardinal Stadium before the Cardinals hit the road to face the Orange of Syracuse on October 21. Louisville defeated both teams last season, winning at Cincinnati, 46-22, and besting Syracuse at home, 41-17.
After an off week on October 28, the Cardinals play a pair of nationally-televised Thursday night contests on ESPN. Louisville hosts West Virginia on November 2 in what will be one of the top games in the entire country. The Cardinals will try to avenge a 46-44 triple overtime loss to the Mountaineers in Morgantown a year ago.
Louisville returns to national television the following Thursday with a visit to Rutgers to face the Scarlet Knights. Louisville defeated Rutgers, 56-5, last year at Papa John's Cardinal Stadium.
After playing on consecutive Thursday nights, the Cardinals return to a regular schedule when the Cardinals host South Florida on November 18. The Cardinals will be out for revenge against the Bulls, who handed the Cardinals a 45-14 defeat last season when Louisville was ranked in the top 10 in the country.
Over the Thanksgiving weekend, the Cardinals will face Pittsburgh at Heinz Field on November 25. Louisville, who defeated Pitt, 42-20, at Papa John's Cardinal Stadium a year ago, will make their first trip to Pittsburgh since 1993.
The Cardinals close out their home and regular season schedule with a visit from Connecticut on December 2. U of L defeated the Huskies, 30-20, on December 3, 2005, in East Hartford.
The Cardinals return 15 starters from last season's 9-3 squad, who fell to Virginia Tech, 35-24, in the 2006 Toyota Gator Bowl.
2006 University of Louisville Football Schedule
Sat, Sep 2 Kentucky
Sat, Sept 9 @ Temple
Sat, Sept 16 Miami (FL)
Sat, Sept 23 @ Kansas State
Sat, Sept 30 bye
Fri, Oct 6 @ MTSU (in Nashville) 8:00pm ESPN2
Sat, Oct 14 Cincinnati
Sat, Oct 21 @ Syracuse
Sat, Oct 28 bye
Thur, Nov 2 West Virginia 7:30pm ESPN
Thur, Nov 9 @ Rutgers 7:30pm ESPN
Sat, Nov 18 USF
Sat, Nov 25 @ Pittsburgh
Sat, Dec 2 Connecticut TBA ESPN or ESPN2