Petrino, who will replace recently fired Jim Mora, agreed to terms on a five-year, $24 million offer from the Falcons front office on Sunday.
In his only head coaching position, Petrino compiled a 41-9 career record at U of L, including a 24-13 win last Tuesday over Wake Forest in the Orange Bowl. The Cardinal program also won the Big East Conference crown this season.
Petrino met with the Louisville players Sunday night to inform them about his decision.
With Petrino's departure to the professional ranks, Tulsa's Steve Kragthorpe is believed to be the frontrunner to become the 20th head coach in U of L football history. It's common knowledge in Louisville that Kragthorpe has been high on the list of U of L AD Tom Jurich for the past few years.
Stay tuned for further developments.