With Georgetown's loss to Syracuse earlier Saturday afternoon, Louisville's win over the Friars moved them into a tie for first place with the Hoyas in the Big East standings at 10-3.
It was a grind it out sort of game for the Cardinals. The contest featured multiple ties and lead changes.
The difference for Louisville: Earl Clark.
The Friars had no answer for the Cardinals 6-9 sophomore forward, who scored 20 points and added 9 rebounds.
Trailing 56-53 with 9:46 remaining in the game, Louisville coach Rick Pitino called timeout. His team responded out of the timeout, gaining the lead and control of the game over the game's next few minutes. When it was over, Louisville had outscored the Friars 27-16 in the contests final nine minutes.
Terrence Williams scored 12 points for Louisville, while David Padgett and Jerry Smith added 11 each. The Cardinals made 29-63 shots for 46 percent shooting for the contest.
It was another solid defensive outing for Louisville, who held the Friars to 35 percent shooting from the floor. The Friars had five players score in double-figures, led by Geoff McDermott's 18 points.
Louisville will take on Syracuse Monday night at Freedom Hall.