In six seasons, Pittsburgh has compiled a 94-9 mark at their on-campus arena. No team, except for Louisville, which has won at Pittsburgh the past two seasons, has won twice in the building.
The Cards have won seven straight in February.
More importantly, Louisville, which is 7-0 in February, kept pace with Georgetown in the Big East standings. The Cardinals and Hoyas are tied for first-place at 12-3.
David Padgett came up big for the Cardinals, scoring 21 points. The 6'11 senior captain made 3 of 4 free throws in the game's final seconds to preserve victory for the Cards.
The Cardinals also received a big boost from sophomore guard Edgar Sosa. Sosa came off the bench for 20 points. Sosa hit 7 of 11 shots, including 3-4 three-pointers.
Louisville scorched the nets against the Panthers, making 58 percent of their field goal attempts from the field.
Despite the Cardinals hot shooting, Pittsburgh forwards Dejuan Blair and Sam Young kept the Panthers in the game. Blair and Young each scored 20 points.
Louisville, which led for much of the contest, took a 42-36 advantage at the break. The Cardinals came out strong in the second half, extending their lead to eight in the first two minutes of the final half. But the Panthers wouldn't fold, cutting Louisville's lead to one twice in the second half.
Clinging to a 52-51 lead at the 10:12 mark, Louisville went on a 7-0 run to open up their margin to eight, 59-51. Derrick Caracter and Padgett both scored on layups, while Sosa drained a three from deep on the baseline.
Louisville kept the Panthers at bay down the stretch, hitting 5 of 7 free throws in the game's final 30 seconds.
With three games left in the regular-season, things don't get any easier for Louisville, though the Cardinals will get their next two games at home.
Louisville will next face. No. 21 Notre Dame Thursday night at Freedom Hall.