Harangody was injured in last Thursday's loss to Seton Hall. He suffered a bone bruise in the second half against the Pirates that forced him to miss the last seven minutes in a 90-87 loss. Harangody also missed Sunday's 69-68 setback at home against St. John's.
"He'll ride the bike today and maybe shoot tomorrow," Brey said on Monday afternoon. "I don't know if we can count on him for Louisville. He said he felt better, but he plays so darn hard that it's got to be right."
Harangody, who is third nationally in scoring (24.1), has caused major problems for Louisville in the past. He dominated the Cardinals inside with 28 points and 13 boards in an overtime loss to the Cardinals last season, then led Notre Dame to a 90-57 win in South Bend last February with a 32-point, 17-board outing. He also scored 40 points against Louisville as a sophomore at Freedom Hall.
If Harangody doesn't play, Notre Dame likely will go small by using a three guard lineup. Jonathan Peoples, a guard who started the Irish's first eight games and is averaging 4.3 points and 2.1 rebounds, started in Harangody's place against St. John's. Peoples didn't score or have an assist in 12 minutes in the loss to the Red Storm.
"We will play the three guards which we started the year with," Brey said. "We've played that way and substituted and played that way for long periods of time."
Both Louisville and Notre Dame are battling for one of the Big East's at-large NCAA Tournament bids. The Cardinals are 16-9 overall and 7-5 in the Big East; Notre Dame 17-9, 6-7. The winner of Wednesday's game will have a clear advantage heading towards the post-season.