Johnny Jones' Tigers kept it close despite losing freshman forward Jarell Martin to an ankle injury 33 seconds into contest.
Johnny O'Bryant led the way for LSU with 23 points and 11 rebounds. Freshman Jordan Mickey also notched a double-double with 16 points and 10 rebounds (and five blocks).
Senior Andre Stringer chipped in 21 more points on 3-of-7 shooting from three-point range.
UMass was paced by senior point guard Chaz Williams, who finished with 24 points and nine assists.
The Minutemen went to the line 15 more times than LSU (40-25) and converted on 70% of their attempts, making the game an up-hill climb for LSU in the second half.
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LSU falls to UMass 92-90