LSU (12-0, 2-0 SEC) jumped out to a 6-0 lead and then put together a 15-0 run to pull away on the way to the program's 16th straight Southeastern Conference victory.
The Lady Tigers also put together a solid defensive performance, holding Auburn (9-5, 0-1 SEC) to just 35.6 percent shooting from the floor, including just 26.1 percent in the second half. Auburn also committed 23 turnovers that were converted into 33 LSU points.
LSU led 40-23 at the break and outscored Auburn 25-15 in the second 20 minutes of action.
"Overall I'm extremely pleased with the outcome of this game," LSU head coach Pokey Chatman said. "As far back as I can remember we have struggled in this building and it was nice to see us not only put together two halves of basketball, but in the manner in which we put it together."
The 27-point victory was the largest margin of victory by an LSU team at Auburn and the second largest margin by the Lady Tigers in the series' history. It just the fifth time LSU has won in Beard-Eaves Memorial Coliseum.
Scholanda Hoston added 15 points, while Quianna Chaney added six points as the only other Lady Tigers player to crack the scoring column.
Nitasha Brown led Auburn with 14 points.
LSU shot 47.5 percent from the floor, including 62.1 percent in the first half. The Lady Tigers out rebounded Auburn 32-31 and were led by Fowles with nine.
The Lady Tigers return home for an 11 a.m. Saturday game with No. 15 Minnesota in a non-conference made-for-TV match-up Pete Maravich Assembly Center. The game is LSU's annual Pack the PMAC promotion.
- Seimone Augustus reached double figures for the 74th straight game with 21 tonight. Augustus also scored at least 20 points for the 54th time in her career.
- Sylvia Fowles reached 20 points for the sixth time this season and the seventh time in her career, finishing the game with 23 points.
- LSU has had at least a 21-point lead in 12 straight games (every game this season but the opener at Texas Tech - 10 point lead was the largest), including leading 38-17 in the first half of tonight's game.
- LSU has now won 16 straight Southeastern Conference games.