The Tigers (4-0, 2-0 SEC) are coming off an open date, while the Gators (4-1, 2-1 SEC) ran their record to 4-1 overall and 2-1 in league play with a 38-7 victory over Arkansas on Saturday.
LSU and Florida meet for 55th time with the Gators holding a 28-23-3 lead in the series.
The Tigers are 10-13-3 against Florida in Gainesville.
LSU has won three of last four and four of last six against the Gators.
The teams are 4-4 over the last eight games dating back to 2000.
LSU goes into the Florida game leading the SEC in total offense (427.2 ypg) and ranking second to Florida in points per game (35.5).
The Tigers are second in the league in rushing offense with 206.5 yards per game.
Defensively, LSU is fifth in the SEC in total defense (260.8 ypg) and sixth in scoring defense (15.2 ppg). The Tigers are allowing 191.8 yards passing per game and just 69.0 yards rushing per game.
Charles Scott continues to lead the SEC with 133.8 yards rushing per game. In four games, he has rushed for 535 yards and six TDs.
Scott goes into the Florida game looking to become the first LSU back to gain 100 yards in Gainesville since 1982 when Dalton Hilliard rushed for 127 yards on 26 carries in a 24-13 Tiger win over Florida in 1982.
By rushing for 100 yards in LSU's first four games, Scott has joined Charles Alexander (1978) and Steve Van Buren (1943) as the only players in school history to accomplish such a feat. Alexander did it in the first four games in 1978 before having the streak snapped in week 5 against Georgia, while Van Buren did in LSU's first seven games in 1943.
Lee’s top target has been that of Brandon LaFell, who leads the SEC in yards per game with 87 and he's third in the league with 5.5 catches per game.
Darry Beckwith is expected to return to action this week after missing games against Auburn and Mississippi State. Defensive lineman Charles Alexander and linebacker Kelvin Sheppard are both expected back after missing practice time last week.
However, Ricky Jean-Francois, did not make the trip according to LSU officials and will miss the game with a groin injury.
Les Miles ranks first in SEC history for wins after 44 games with 38. Miles' 38 wins puts him ahead of such names as Mark Richt (35), Steve Spurrier (34) and Bernie Moore (33).
An LSU win on Saturday will give the Tigers back-to-back 5-0 starts for the first time since 1972-73. LSU won its first seven games in 1972 and followed that by winning nine in a row to open the 1973 season.
LSU has scored at least 21 points in every game (28 straight) since their last trip to the Swamp when Florida held the Tigers to 10 points in a 23-10 win over LSU
Florida won its last game against a defending national champion on Sept. 18, 1999, with a 23-21 win over Tennessee. UF is 3-11-2 against defending national title winners. The other two wins came against Alabama in 1927 (13-6, Nov. 12) and against the Crimson Tide in 1993 (28-13, Dec. 4).
Against Arkansas, 246 of UF’s 514 yards of total offense came in the fourth quarter. In addition, Florida has allowed three teams only one first down in the fourth quarter this year (Miami, UT, Ole Miss).
In its last outing, Florida rushed for 278 yards against Arkansas. The total was the most for the Gators in an SEC game under Coach Meyer and the third-best overall effort.
Florida’s running backs have accounted for 532 yards on 76 carries (7.0 yards per carry) and they have six touchdowns. In 2007, the Florida running backs carried the ball 136 times for 761 yards and six rushing touchdowns. As a group, they averaged 5.6 yards per carry.
In two games against the Tigers, Tim Tebow is 14-of-28 passing for 194 yards and four touchdowns. He has run 25 times for 102 yards and two touchdowns.
Since 2006, Tebow is one of two players in the nation to have accounted for six touchdowns against LSU (Darren McFadden, Arkansas).
Percy Harvin has scored a touchdown in each of the last seven games he has played in. In the last seven games he has played in, Harvin has touched the ball 109 times for 1,150 yards (10.6 yards per touch) and has had 10 touchdowns.
Florida’s passer rating at home since 2005 (165.2) ranks fourth in the nation and first in the SEC since 2005 (Louisville, 167.9).
Over the past four seasons, UF has ranked first in the SEC and fifth in the nation in rushing defense allowing just 90.8 yards per game. Only one other SEC team ranks in the top 10 in the category during the span (LSU, ninth, 95.8).