Quinn Stewart gave the Tigers two more runs as he took a Ryan Schwabe pitch over the left field wall for his second home run to give the Tigers a 3-0 lead.
"It was a change-up and he left it over the plate so I jumped on it," Stewart said.
A fifth-inning Joey Wolfe solo home run would put Louisiana-Monroe (5-2) on the board but the Tigers answered in another three runs in the bottom of the inning that was capped by a two-run double by Jon Zeringue.
LSU would put the game out of reach in the eighth as an RBI triple by Ivan Naccarata and a RBI double by Holt pushed the LSU lead to 9-4.
Justin Meier (2-0) was impressive on the mound for the Tigers as the freshman right-hander went five innings and only allowed one run on three hits.
"I just kept hitting my spots," Meier said. "I just have to keep the ball low and let the offense due their job."
"It was nice to see Meier throw nice back-to-back games," Laval said.