Jacory Harris completed just 9-of-25 passes in the first half but ended up with over 200 yards and one touchdown, along with one score on the ground.
Damien Berry, once again, ran for over 100 yards and scored a touchdown in the second quarter. He did lose a fumble for the second week in a row, though.
The Hurricanes held Duke's offense to under 300 yards of offense, had seven turnovers, had nine tackles for loss, three sacks, and had a Micanor Regis interception return for a touchdown.
The win pushed Miami's record to 4-2 overall and 2-1 in the conference. The team will play host to North Carolina next Saturday night.